Brain Disease: Growing Cases of Brain-related Diseases and Disorders across the Globe

Addictions (Substance Use Disorders) are extremely powerful.  So much so that even after years or decades of abstinence and recovery, an individual can still experience strong cravings, and be vulnerable to relapse.  Neuroimaging has allowed researches to investigate the acute and long-term effects of addiction on the brain.  The majority of addiction experts agree that addiction greatly impacts the brain, and many have coined it a “brain disease.”

Individuals who have developed addictions often struggle with impulse control.  This is why the risk and rate of relapse is so high among individuals who enter recovery.  Approximately 40-60% of individuals who are in a 30-day inpatient rehab for drug and alcohol abuse relapse within the first 30 days of leaving, and up to 80% relapse within the first year.  Impulse control is a primary factor that contributes to such high relapse rates.

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According to the American Cancer Society, about 23,890 malignant tumors of the brain or spinal cord are estimated to be diagnosed across 2020. These statistics are alarming and apart from this type of brain disease, many other disorders are having nearly similar statistics.

We all understand that the brain is an essential component of the human body. It is the central control hub for all our bodily function, so if it is in crisis, the effects can be devastating. Under the umbrella of brain diseases, there are many individual variations, all vary widely depending on the particular condition. Brain diseases can result in other comorbid conditions such as paralysis, seizures, and comas.

1. Meningitis

Meningitis is the inflammation of the lining that surrounds the brain and the spinal cord. Usually due to infection, bacterial and viral meningitis are the two most common forms of the disease. However, other cases are known to be caused by fungi, chemical irritations, drug allergies, and some cancers. The inflammation can be deadly serious if left untreated and complication can occur such as seizures, brain damage, and hearing loss. Symptoms can vary depending on age and the type of meningitis, but hospitalization is the most immediate action in these cases as early diagnosis can prevent further complications.

2. Alzheimer's Disease

Dementia and Alzheimer's disease are similar, but not the same thing, as they are often mistaken to be. Alzheimer's is a form of Dementia. With Dementia, there is a decline in cognitive function. This is due to death, damage or malfunction of brain cells brought on by strokes, alcohol abuse, and other conditions. Alzheimer's Disease kills and destroys brain cells. They begin to degenerate or form an abnormal tissue build up. This causes progressive memory loss and changes in behavior and personality. These conditions are a combination of genetics, lifestyle, and environment , but it is not entirely clear exactly what causes it.

3. Epilepsy

Epilepsy is a seizure disorder and is one of the most common neurological disorders in the world. Its main trait is unpredictable seizures that range in severity, but they can cause many other health problems as well. A seizure is the disruption of any electrical communication between neurons in the brain. Epilepsy is a chronic noncommunicable disorder of the brain. To diagnose epilepsy, a person must experience two or more unprovoked seizures, separated by at least 24 hours.

4. Brain tumor

A brain tumor any mass of abnormal tissue cells, which form a growth inside the brain. These growths can be benign (non-harmful) or malignant (cancerous). Either way, they can cause problems by the pressure they cause onto the brain. Tumors grow because more and more cells combine into the mass. As it grows in size, the risk of seizure, motor function disruption and confusion grows. Doctors can treat cancerous tumors or remove them depending on location and size. Treatment is not always required in the case of benign tumors, unlike cancerous tumors, they will not spread to other parts of the body.

5. Lou Gehrig's Disease

Amyotrophic lateral sclerosis (ALS) is the medical name of Lou Gehrig's disease. The name of this diseases refers to Lou Gehrig who was a famous baseball player in the 1930's. Gehrig suffered from muscle atrophy. Lou Gehrig's disease is a neurodegenerative disease, which affects the brain and spinal cord, specifically the sections of nerve cells, which signal and controls muscles. The motor neurons die, and the nerve area scars or hardens, which is where sclerosis comes from. Sporadic ALS is the most common form of the disease with up to 90% of cases diagnosed, and familial ALS, which counts for 5-10%.

Leading companies operating in this research are Pfizer, Eli Lilly, F. Hoffmann La Roche AG, Janssen Pharmaceuticals, Abbvie, Allergan, Merck and Co, Novartis AG, AstraZeneca


References: 

https://www.familyaddictionspecialist.com/blog/why-is-addiction-called-a-brain-disease-by-many-addiction-professionals

http://www.acupuncturehealthcentertexas.com/Brain-Diseases.html

https://www.theinsightpartners.com/reports/brain-disease-market 


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