Increasing Awareness Related to the Stem Cells Therapy in Effective Disease Management
Stem cells are preliminary body cells from which all other cells with specialized functions are generated. Under controlled environment in the body or a clinical laboratory, these cells divide to form more cells called daughter cells. Due to the advent of modern health science, these cells play a major role in understanding the occurrence of diseases, generation of advanced regenerative medicines, and drug discovery. There are certain sources such as embryo, bone marrow, body fats, and umbilical cord blood amongst others, where stem cells are generated.
Researchers are further investigating stem cell therapy in autoimmune disorder. Other adult stem cells based treatments are under clinical trials. Hematopoietic stem cells are currently used for treating more than 80 medical diseases, which include diseases of the immune system, blood disorders, neurological disorders, metabolic disorders, genetic disorders, and several types of cancers like leukemia, lymphoma, etc.
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Alzheimer's disease is believed to have strong genetic
etiology. But, lifestyle and environmental factors may also contribute to the
disease’s development. In addition to
memory loss, patients with Alzheimer's experience difficulty in reasoning and
decision making. Some patients may report mood swings, social withdrawal, and
delusions.
Recent strides in stem cell technology mean that quality,
consistency, activity, and safety can be assured, and that it is possible to
grow essentially unlimited amounts of dopamine-producing nerve cells in the
laboratory for transplantation. This approach is now rapidly moving into
initial testing in clinical trials. The choice of starting material has also
expanded with the availability of multiple human embryonic stem cell lines, as
well as the possibilities for producing induced pluripotent cells, or neuronal
cells from a patient’s own blood or skin cells. The first systematic clinical
transplantation trials using pluripotent stem cells as donor tissue were
initiated in Japan in 2018.
Leading companies operating in the stem cell therapy are
Medipost, pharmicell Co., Ltd., Holostem Terapie Avanzate S.R.L., Mesoblast
Ltd., U.S. Stem Cell, Inc., Biotime, Inc., RichSource, Caladrius, TiGenix NV
(Takeda Pharmaceuticals), and Genea Biocellsamong others.
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